The “2nd International Workshop on Human-Centric Smart Environments for Health and Well-being (IHSH’2020)” will be held at the Faculty of Technology of the University M’hamed Bougara of Boumerdes (Algeria) on February 9-10th, 2021. The workshop will provide an interesting multi-disciplinary collaborative forum for the active community of academics, researchers and industrials from computer science, information technology, electrical engineering, biomedical engineering, and telecommunication. The workshop invites authors for presenting original works describing research results, theoretical, practical or industrial solutions (prototype, formal modeling, augmented reality, machine learning, big data, web & internet of things, system theory, optimization, robotics, etc.) and discussing innovative ideas that have potentials to build human-centric smart environments for health and well-being. The workshop will include plenary talks and oral/poster sessions.